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Memory loss at 30, 40 or 60: 12 causes, most of them treatable

Forgetfulness and short-term memory loss have many causes besides dementia: sleep, stress, depression, thyroid, B12, medicines and more. When to worry, and what to check.

By Arshi Niyaz, Co-founder & CSO7 min read
A cloud with a brain and a moon: brain fog, sleep and memory

Quick answer

Most memory slips, especially under 60, are caused by something other than dementia: poor sleep, stress, anxiety or depression, thyroid problems, low vitamin B12, alcohol, medicines, hearing loss, or another illness. Many of these are treatable. See a doctor if forgetfulness is getting worse, affects work or daily life, or comes on suddenly.

What is the most common cause of forgetfulness?

In younger adults, the most common causes are poor sleep, stress, anxiety and depression, followed by medicine side effects, alcohol and medical problems such as thyroid disease or low vitamin B12.

12 causes of memory loss

  1. Poor or short sleep, including sleep apnoea.
  2. Stress and anxiety.
  3. Depression.
  4. Underactive thyroid.
  5. Low vitamin B12 or folate.
  6. Medicines, such as some sleeping tablets, antihistamines and bladder medicines.
  7. Alcohol and recreational drugs.
  8. Hearing or vision loss.
  9. Infections, especially in older adults (this can cause sudden confusion, called delirium).
  10. Head injury.
  11. Stroke or small vessel disease.
  12. Neurodegenerative conditions, such as Alzheimer's disease.

Is it normal for memory to get worse at 30?

Occasional slips are normal at any age, especially when tired or busy. A steady decline at 30 or 40 is not typical and is worth a doctor's visit, mainly to look for treatable causes such as sleep problems, depression, thyroid disease or B12 deficiency.

Brain fog

Brain fog is not a diagnosis but a description: slow thinking, poor focus and forgetfulness. It is common after viral illnesses, with poor sleep, during menopause, and with stress. If it lasts more than a few weeks, see a doctor.

How to improve memory

  • Sleep 7 to 9 hours and keep a regular schedule.
  • Exercise most days.
  • Treat hearing loss.
  • Limit alcohol.
  • Write things down and use reminders: it frees attention for remembering.
  • Keep socially and mentally active.

Frequently asked questions

  • It is worth checking if it is getting worse, affects work or daily life, worries family members, or came on suddenly.

  • Yes. Stress and anxiety affect attention and the storing of new memories. Memory usually improves when stress is treated.

  • Low vitamin B12 is the best known. Low folate and vitamin D are also checked.

  • Start with your family doctor, who can refer you to a neurologist, psychiatrist or memory clinic.

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Sources

  1. 1.Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission. The Lancet, 2024.
  2. 2.Alzheimer's Disease Fact Sheet. National Institute on Aging, 2023.
  3. 3.Dementia fact sheet. World Health Organization, 2023.

This article is for information and does not replace advice from a doctor. If you notice changes in memory or thinking, see a doctor.